ABSTRACT
Introduction: The posterior cranial fossa is the largest and the deepest of the three fossae. Contents of posterior cranial fossa include occipital part of cerebral hemispheres, cerebellum, midbrain, pons and medulla oblongata. Variations in the volume of posterior cranial fossa may cause compression of these structures which may lead to various disorders. There is increasing evidence on the diagnostic potential of posterior cranial fossa measurements. The present study on morphometry of posterior cranial fossa based on CT images of patients without any clinical abnormality was undertaken for the first time in south Indian population. Subjects and Methods: To study and compare sex-wise and age-wise differences in the supratentorial and posterior cranial fossa (PF) measurements in the normal CT scan images of 62 males and 38 females who attended the Neurology department of SVIMS belonging to Rayalaseema region was undertaken. The measurements that were recorded are transverse diameter (TD) and anteroposterior diameter (APD) of supratentorial part and also posterior cranial fossa and height and volume of posterior cranial fossa. Results: The mean supratentorial TD and APD were found to be less in male but were not statistically significant sex-wise and age-wise. The mean posterior fossa APD was significant, PF height and volume were highly significantly in males. Discussion: There are no reports on supratentorial parameters in literature for comparing the results of present study. Except for one study on CT on height and volume of posterior cranial fossa there are no other studies for comparing the values of present study. Conclusion: Observations on supratentorial parameters of the present study are the first to be reported in literature.Age-wise and sex-wise observation of parameters of TD and APD of PF are the first to be reported in literature.
ABSTRACT
Introduction: Female reproductive system cancers shorten lifespan in women because of high mortality and morbidity. The detection of pre-invasive and micro-invasive stages makes near 100% survival of cancer patients. Dermatoglyphics is the scientific study of fingerprints. Many genes which take part in the control of finger and palm dermatoglyphic development distinguished cancer patients from the general population. It is possible that these genes also predispose to the development of malignancy. Since many investigations are needed to confirm the diagnosis of cancers, dermatoglyphics can be used as a screening procedure for planning preventive care if a specific pattern is known for a cancer. Aims and Objectives: To analyze the prints of different cancers, to analyze the results, compare with controls and observe the differences in main parameters of dermatoglyphic patterns and to determine a specific pattern for specific cancers. Subjects and Methods: This is a prospective, observational and an analytical study started after the approval by Institutional Ethical Committee of S.V. Medical College, Tirupati. The material for the study consisted of finger and palm prints of outpatients and inpatients of the Department of OBG, Tirupati, Cancer Hospital in and around Tirupati, Nellore and Kadapa. The ink prints of each finger and palm were collected and analyzed. Results: Ridge counts, digital patterns and main line formulae observed in different cancers in the present study were analyzed and presented. Mean TFRC was higher in normal group. Greater AFRC was observed in cancer cervix patients when compared to controls. In the present study, there is no difference (p> 0.05) in a-b ridge count among carcinoma of cervix and control group in both hands. Differences of mean atd, tad and tda angles among the groups are not statistically significant (P>0.05).The most common C-main line termination pattern of cancers are U followed by R and then Ab. IV interdigital area of both hands presented less incidence of loop pattern in cancer cases when compared to normal group. Special findings in respective cancers are discussed separately and they are not found in any other literature. Conclusion: There are very limited studies in literature on dermatoglyphic pattern in female reproductive cancers. Though the cost of prints is less, more time and skilled human resources are required for their analysis. Study sample size of controls and cases to be increased. Public should be enlightened about dermatoglyphics. If large number of studies are done and a specific pattern is established for specific cancers, then it becomes cost-effective to people so that a risk is predicted beforehand in any disease and preventive methods can be employed at an early age as the dermatoglyphic patterns do not change in a life time.